Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy

Authors

Layla Othman Farhan, Department of Chemistry , College of Science for Women, University of Baghdad, Baghdad, Iraq.Follow
Baydaa Ahmed Abed, National Diabetes Center, Mustansiriyah University, Baghdad, Iraq.Follow
AshganSlman Dawood, Department of Chemistry , College of Science for Women, University of Baghdad, Baghdad, Iraq.Follow

Abstract

The current study was designed to compare some of the vital markers in the sera of diabetic and neuropathy patients via estimating Adipsin, Fasting blood Glucose(FBG), Glycated(HbA1c) hemoglobin, Homeostasis Model Assessment Index (Homa IR ), Cholesterol, High density lipoprotein (HDL), Triglycerides (T.G), Low-density, and lipoprotein (LDL), Very Low Density Lipoprotein (VLDL), in sera of Iraqi patients with diabetes and neuropathy. A total of ninety subjects were divided into three groups: group I (30 diabetic with neuropathy males) and group II (30 diabetic males without neuropathy), and 30 healthy sujects were employed as control group. The results showed a significant decline in Adipsin levels (p>0.05) in neuropathy, T2DM group with respect to the control group, while, no changes were recorded within both diabetic patients groups .The serum insulin level dropped considerably in neuropathy, T2DM group in a comparison with control group. The Adipsin ROC curve showed a clear cut-off value (4510.813, 3967.08) when calculated in neuropathy, T2DM respectively. The study concluded that Adipsin is a diagnostic factor for T2DM with neuropathy

Keywords

Adipsin, Homa IR, Insulin, Neuropathy, Type 2 diabetes

Article Type

Article

How to Cite this Article

Farhan, Layla Othman; Abed, Baydaa Ahmed; and Dawood, AshganSlman (2023) "Comparison Study between Adipsin Levels in Sera of Iraqi Patients with Diabetes and Neuropathy," Baghdad Science Journal: Vol. 20: Iss. 3, Article 23.
DOI: https://doi.org/10.21123/bsj.2022.7408